For example, the terms cardiac muscle contraction or regulation of ventricular cardiac muscle cell depolarization were enriched for Cardiac Arrhythmia, including genes such as Gap Junction Protein Alpha 1 (GJA) and T-Box Transcription Factor 5 (TBX5) with known roles in the disease [40, 41]. The gene discussed is GJA1; the disease is cardiac arrhythmia.