Consistent with these findings we observed higher expression 8 days post-MI of both Mb and Tnni3, encoding respectively myoglobin and troponin I cardiomyocyte-specific genes in GSK-343-treated mice, suggesting limitation of cardiomyocyte cell death or dysfunction in the border zone (Fig. 6b). Here, TNNI3 is linked to myocardial infarction.