As much evidence regarding the consumption of vitamin D has shown, this vitamin could decrease the risk of severe ARDS in COVID patients by decreasing the production of Th1 cells, reducing the inflammatory cytokines generation such as IL-6, IL-8, IL-12, and IL-17, TNFα and inhibits gamma interferon (IFN-γ) and IL-2 to reduce cytokine storm syndrome [4, 12]. The gene discussed is TNF; the disease is acute respiratory distress syndrome.