CD274 and neoplasm: Three of 10 patients (patients 1, 6, and 8), each of whom had carboplatin-pretreated disease metastatic to lymph nodes, as well as in bone (n = 1), and whose pre-PIKTOR tumor biopsies were PD-L1-negative by IHC (n = 2) or PD-L1-positive (n = 1), had durable SD on single agent pembrolizumab following PIKTOR and cis/nab pac therapy for 106, 190 and 65 weeks, respectively.