We then carried out detailed analyses at the protein level of the expression of these and other ferroptosis markers in CH-EAE that regulate intracellular iron (TfR1, DMT1, HO-1, ferritin and NCOA4), glutathione (GPX4 and xCT) and membrane lipid repair enzymes (ACSL4 and LPCAT3). The gene discussed is GPX4; the disease is cyclic hematopoiesis.