MIB1 and neoplasm: Variables that were controlled for included patient sex [7, 17, 24], age [7, 14, 15, 17, 24], tumor location [7], primary/recurrent tumor [7, 14, 15, 24], extent of resection/Simpson grade [7, 13, 17, 32], WHO grade [7, 13, 17, 24, 32], histopathological subtype [7], adjuvant radiotherapy administered [7], Ki-67/MIB1 proliferation index [7, 13–15], number of mitoses [15], and expression of the histone modification system EZH2 [32].