In the present study, we used age, gender, never smoker, hypertension, EGFR mutation, histology, tumor stage, ECOG PS score, number of metastases, number of previous treatment lines, number of previous chemotherapy lines, previous targeted therapy, previous radiotherapy, previous immunotherapy, anlotinib monotherapy, leukocyte, neutrophil, lymphocyte and platelets as stratification variables, of which only ECOG PS score was identified. Here, EGFR is linked to Hypertension.