CRP and malaria: We hypothesize that the clinicians in the intervention arm may have been uncomfortable withholding an antibiotic—as guided by a strict interpretation of the algorithm (Figure 1, Tables 4 and 5)—in the face of an elevated CRP (and/or CBC) result (Table 6), which may be seen in malaria-positive patients, leading to higher-than-usual antibiotic prescribing in this subgroup.