CSF1 and Schnyder corneal dystrophy: Furthermore, CSF-1 signals were essentially undetectable in all circulating monocyte subsets of sickle mice (data not shown), in line with the minimal CSF-1 transcripts (5 fragments per kilobase per million mapped fragments [FPKM], compared with HLA-DR transcripts of 1892 FPKM) observed in RNA-Seq analysis of human SCD peripheral blood CMo (Supplemental Figure 2D) (25).