To establish the relationship between CSF-1 and PMo numbers in patients with SCD, we conducted correlation analyses, but surprisingly, no association was found (Figure 3A, R = 0.19, P = 0.31; see gating strategies in Supplemental Figure 3A), suggesting a role for other factors that may affect CSF-1 control of PMo numbers in SCD. Here, CSF1 is linked to Schnyder corneal dystrophy.