FGF23 and enthesopathy: Deletion of FGF23 in mice resulted in a mild, though nonsignificant, decrease in enthesis BMP and IHH signaling compared with WT, whereas deletion of Fgf23in Hyp mice restored normal BMP and IHH signaling in Hyp entheses, suggesting actions specific to FGF23 or actions downstream of FGF23, such as decreased 1,25D production, regulate enthesopathy development.