Yet, there was no significant difference between SCH group and euthyroid controls regarding; S. Osmol, U. Osmol, serum Na + , Urine Na + , FENa %, serum K + , urine K + , FEK %, Renin/Aldosterone ratio, S/U(Na/K), and CPP. The gene discussed is REN; the disease is spindle cell hemangioma.