IGHE and anaphylaxis: Inclusion:1.Age 1–10 yrs,2. Weight >7 kg,3. +ve DBPCFC,4. +ve SPT (wheal>3 mm) or peanut specific IgE ≥0.35kU/LExclusion:1. Severe anaphylaxis or during DBPCFC2. FEV1 <85% pred3. FEV1/FVC <85% pred4. chronic persistent asthma5. cardiac disease6. Beta blockers or ACE7 GI disorders8. Recent surgery9. Recent probiotics10. Major illnesses11. Unable to follow protocol12. Many others