Thirty days after subcutaneous injection of control (Mneo) or Bcl-xL overexpressing (Mxl90) M14 melanoma cells in immunodeficient mice, the presence of macrophages infiltration was analyzed by IHC analysis using F4/80 and CD206 antibodies, the former being a specific murine macrophage related marker and the latter a specific M2 macrophage marker. The gene discussed is BCL2L1; the disease is melanoma.