CXCL8 and cutaneous melanoma: Our findings are in agreement with those demonstrating (i) IL-1β ability to regulate macrophage functions [47, 48], (ii) the ability of IL-8 neutralization to attenuate the promoting effect induced by GC-MSCs on M2-like macrophage polarization [49], (iii) correlation of CCL5 expressions with infiltration of macrophages in cutaneous melanoma [50].