DEGs analysis showed that the expression of IFN-γ in γδT cells was significantly increased (fold change = 4.92) in CeD duodenal tissue (Fig. 6D, Additional file 8: Table S7), suggesting that the cells were an important source of IFN-γ, and might partly contribute to the activation of duodenal IFN-γ pathway in CeD patients. Here, IFNG is linked to cranioectodermal dysplasia.