As LAMP3+ DCs exhibited increased expression of genes encoding a co-stimulatory molecule such as CD40, which is associated with interaction between myeloid cells and T cells28, and IL12B, which promotes TH1 development29(Extended Data Fig. 6a), we speculate that LAMP3+ DCs might also help potentiate the infiltration and differentiation of TH1-like cells in ovarian tumors. The gene discussed is CD40; the disease is ovarian neoplasm.