PREB and infection: Similar results were obtained in a third assay in which viral particles were pre-incubated with sEC1-2 in solution as above, and then exposed to PCDH1-bearing target cells (Fig. 2e): both sEC1-2(WT) and sEC1-2(F83L) could block rVSV-ANDV-Gn/Gc infection, but the latter was less active (Fig. 2f).