Gene expression correlation analysis of 207 human lung cancer cell lines using the DepMap data explorer (43) revealed that GRP78 is positively correlated with EGFR at the mRNA level (P = 2.4e-13, R = 0.48) (Fig. 2A), suggesting that GRP78 may regulate EGFR expression at the transcriptional level. Here, EGFR is linked to lung carcinoma.