TNF and Stroke: We found that the ischemic hemispheres of Tmem119-CreERT2; Nr4a1fl/fl mice at 24 h after stroke expressed more Tnf mRNA than those from Nr4a1fl/fl mice, whereas the mRNA expression of Il1b, Il6, Il10, and Tgfb1 did not show any significant changes (Figs 6A–6D and S5A).