In addition to detecting pathogenic variants in genes previously linked to polymicrogyria (eg, ADGRG1/GPR56, SCN3A, TUBB2B), we discovered 6 genes linked to polymicrogyria for the first time (QRICH1, TMEM161B, PANX1, KIF26A, SCN2A, and MAN2C1). Here, TUBB2B is linked to polymicrogyria.