Sequencing of our cohort identified polymicrogyria cases associated with de novo variants in SCN2A, as well as rare inherited variants in TMEM161B, KIF26A, and MAN2C1. Details of these associations have been recently reported (TMEM161B,34MAN2C1,35KIF26A,36 and SCN2A9). The gene discussed is SCN2A; the disease is polymicrogyria.