Recently, Song et al. found Golgi phosphoprotein 3 (GOLPH3) was overexpressed in NSCLC tissues, and promoted the secretion of exosomal WNT3a and activation of canonical WNT pathway via increasing exosome-localized cytoskeleton-associated protein 4, thus enhancing the metastasis and CSC-like phenotype in NSCLC [81]. The gene discussed is CKAP4; the disease is non-small cell lung carcinoma.