SLC7A7 and osteoporosis: Given the growth failure and delayed skeletal development in Slc7a7Lbu/Lbu mice and the role of Slc7a7 in osteoblast differentiation in cell studies (Shen et al., 2021, 2022), we hypothesized that loss of Slc7a7 in osteoblasts might impair growth and skeletal development and contribute to osteoporosis in LPI.