Our results also showed that in accordance with other studies, in western Mexico ‐173 MIF polymorphism GG genotype is the most recurrent (Castañeda‐Moreno et al., 2018; Llamas‐Covarrubias et al., 2013), but contrary to expectations, the CC genotype may be considered a lower‐risk factor (OR = 0.18, p = 0.02), whereas other authors have reported an association between the C allele and an increased risk of cancer (Vera & Meyer‐Siegler, 2011), especially in prostate cancer (Ding et al., 2009; Razzaghi et al., 2019). Here, MIF is linked to Familial prostate cancer.