The results of correlation analysis between PSMD2/3/5/7/13/14 methylation sites and gene expression from the TCGA dataset (GBM samples, n = 701) are shown in Figure S5C. As an example, the results revealed that cg00306249 and cg09604352 are the most likely methylation sites regulating PSMD2 expression, and cg09586646 is the most likely methylation site regulating PSMD5 expression (Figure S5C). The gene discussed is PSMD5; the disease is glioblastoma.