NES and colorectal carcinoma: Subgroup analysis showed that higher nestin was associated with worse OS of GC (HR: 1.46, 95% CI: 1.23 to 1.74, P < .001, I2 = 0%) and LC (HR: 2.05, 95% CI: 1.66 to 2.52, P < .001, I2 = 0%), but not CRC (HR: 1.03, 95% CI: 0.69 to 1.53, P = .89, I2 = 0%) or PC (HR: 0.96, 95% CI: 0.72 to 1.28, P = .80, I2 = 26%; P for subgroup difference < .001; Figure 2B).