Early life hyperoxia exposure enhances innate lymphoid cell (ILC2) function by increasing the expression of IL-33, and ILC2s produce type 2 cytokines such as IL-5, IL-13, and mediators involved in tissue repair, leading to eosinophilic airway inflammation and airway remodeling (Iijima et al., 2021). Here, IL13 is linked to inflammatory response.