Previous studies provide support for the diagnostic and prognostic roles of a series of serological indicators in HBV-associated liver diseases, such as C-reactive protein (CRP) [6], CRP to albumin ratio (CAR) [7, 8], albumin-bilirubin score (ALBI) [9], aspartate aminotransferase to platelet ratio index (APRI) [10], fibrosis index based on four factors (FIB-4) [11], gamma-glutamyl transpeptidase-to-platelet ratio (GPR) [12], and gamma-glutamyl transpeptidase-to-albumin ratio (GAR) [13]. The gene discussed is CRP; the disease is liver disorder.