YTHDF2 and type 2 diabetes mellitus: Some studies have reported that YTHDF2 and eIF3G are upregulated in T2D model mice (83), high-glucose-induced HepG2 cells had upregulated Ythdf1 mRNA (92), and high level of ROS in vivo can increase the level of Ythdf2 mRNA (81), but there is no explanation for these results.