YTHDF1 overexpression is related to enhanced adipogenesis (73), while YTHDF2 degrades the corresponding genes’ mRNA that recognize the m6A modification sites affected by methylases and demethylases (55, 58); only YTHDF3 has been reported to be associated with obesity (74). This evidence concerns the gene MBD2 and obesity due to melanocortin 4 receptor deficiency.