TINCR and familial dilated cardiomyopathy: Methyltransferase METTL14 was down-regulated in the hearts of rats with DCM (T1DM-induced) and enhancement of its expression inhibited pyroptosis in myocardial tissues and improved systolic function (increased fractional shortening and ejection fraction) via down-regulation of lncRNA Tincr. The expression of Tincr was regulated in a YTHDF2-dependent manner (94).