10. Acute stress diseases, such as shortness of breath, fever and diarrhea, severe leukopenia, malignant tumor, liver dysfunction (bilirubin> 1.5 times the upper limit of normal value, alanine aminotransferase> 2 times the upper limit of normal value) or organic diseases, such as decreased renal function eGFR*<20 mL/min/1.73 m2. The gene discussed is GPT; the disease is Decreased liver function.