Cytokines have an important function in host defense; Abdel-Hamed et al. in 2020 in Egypt, studied the role of gamma-interferon in co-infections and in particular in co-infections of SARS-CoV-2 with digestive parasitizes, high levels of gamma-interferon (50, 13pg/ml) have been observed in mild cases and low levels (0.7385pg/ml) in severe cases of co-infection of COVID-19 with parasites [23]. Here, IFNG is linked to coinfection.