The ATMP5 upregulated the expression of 16 genes in the MDA-MB-231 cancer cell, including BAD, BAX, BIK, BID, BCL10, CASP3, CASP6, CASP7, CASP8, CASP9, CASP14, FAS, MCL1, TP53, and TP53BP2 and downregulated the expression of BCL-2 and BCL2A1. The gene discussed is CASP8; the disease is cancer.