APOE and dementia: In two studies (Hu et al., 2022; Eskelinen et al., 2009) that included less than 40% APOE ε 4 carriers, tea intake can reduce the risk of dementia by 22% (Table 2, RR = 0.78, 95% CI [0.26–2.35], I2 = 73%, p = 0.06).