In the study of induced lupus erythematosus in mice with different pigments, compared with white fmod+/+ mice, the black fmod+/+ produced low levels of FMOD, while white fmod-/- mice developed more severe inflammation accompanied by increased numbers of DCs (97), which indicate that FMOD may be involved in the inflammation of lupus erythematosus by regulating the expansion of inflammatory DCs. Here, FMOD is linked to lupus erythematosus.