Given decreased expression of AUF-1 in COPD epithelium (48), changes in the 494 RIP-Seq-derived AUF-1 target mRNAs levels were investigated in multiple transcriptomic studies of airway bronchiolar epithelium, to further study the potential impact of AUF-1 regulation in airway epithelial responses. Here, HNRNPD is linked to chronic obstructive pulmonary disease.