In addition, MS patients presented lower percentages of memory cells, such as effector memory CD4+ T cells (CD4 TEM) (p=0.0222), central memory CD4+ T cells (CD4 TCM) (p=0.0071), CD20+ memory B cells (MemB1) (p=0.0175), CD19+ memory B cells (MemB2) (p=0.0474) and class-switched memory B cells (CS MemB) (p=0.0034). The gene discussed is RND3; the disease is myeloid sarcoma.