showed that the expression of non-coding RNA sirt1 antisense (sirt1 AS) was significantly reduced in bleomycin (BLM)-induced pulmonary fibrosis and that sirt1 AS effectively inhibited the TGF-β1-modified epithelial-to-mesenchymal transition (EMT) in vitro and alleviated the progression of IPF in vivo (70). The gene discussed is SIRT1; the disease is pulmonary fibrosis.