NK cells migrate to the lungs in response to increased cytokine expression [Tumor necrosis factor alpha (TNF-) and IL-6] from the COVID-19 infected pulmonary epithelial cells resulting in interferon gamma (IFN-γ) mediated lysis as well as antibody mediated cellular cytotoxicity (ADCC) via S-protein triggered killing of virus infected host cells (8). The gene discussed is IFNG; the disease is COVID-19.