Among them, those showing a deregulation at the mRNA level (RNAseq-data) and therefore with a possibly higher impact on impairing protein function were closely evaluated (Supplementary Table 2, bold: AKT1, GNL2, DOCK7, FLG, PLD2, ZNF236, FEM1A, LRRC75B, MAST4, EIF4G3, NBPF10, PLXNA2, MUC5B, PUS3, VPS35L, SF3B3, RACK1, HLA-A, HLA-C) regarding its potential impact on cancer cell stemness or resistance to ionizing radiation. This evidence concerns the gene VPS35L and cancer.