IDO1 and neoplasm: Glycoprotein-A repetition predominant (GARP), a surface molecule of regulatory tumor cells and T-cells),IL10Indoleamine 2,3 dioxygenase (IDO-1), a tryptophan catabolism enzymeArginase (produced by MDSCs)Programmed cell death protein and its ligand (PD-1/PD-L1) and Fibrinogen like protein-2 (FGL2)