NFKB1 and neoplasm: The results showed that these genes play a role in the processes and pathways of pyroptosis, apoptosis, necrosis, inflammatory reaction, cytokine secretion, NIK/NF-κB signaling, NOD-like receptor signaling pathway, cytoplasmic DNA sensing pathway, antigen processing and presentation, etc. At present, studies have shown that NF-κB can regulate tumor angiogenesis and invasiveness (23).