After immunohistochemical staining of normal kidney tissues of 65 patients with cancer tissues (Figure 7A) and adjacent tissues (Figure 7B) in the First Affiliated Hospital of Xinjiang Medical University, it was found that the expression of GSDMD in cancer tissues was significantly higher than that in adjacent tissues (Figure 7C) (n = 65, p < 0.0001). The gene discussed is GSDMD; the disease is cancer.