On the other hand, the estrogen signaling pathway (hsa04915, Figure 4A) was annotated in luminal B BC, and the p53 (hsa04115, Figure 4C), PPAR (hsa03320, Figure 4D), and MAPK signaling pathways (hsa04010, Figure 4D) were annotated in TNBC. Here, TP53 is linked to breast cancer.