Among which three genes, EXOC6 (Padj|ESCC=7.30×10-3, Padj|GC=6.00×10-4, Padj|CRC=2.6×10-2), LRP5L (Padj|ESCC=2.70×10-3, Padj|GC=5.70×10-3, Padj|CRC=1.65×10-2), MIR1263/LINC01324(Padj|ESCC=3.22×10-2, Padj|GC=4.36×10-2, Padj|CRC=3.26×10-2) were statistically significant in all three cancer types. This evidence concerns the gene LRP5L and cancer.