Upon h-α-CGRP infusion, 26 of 31 (84%) of healthy participants reported headache (12, 23), three of 41 (7%) healthy participants reported migraine-like headache (12, 15, 23), and 96 of 153 (63%) participants diagnosed with migraine reported migraine-like attacks (11, 12, 15–18, 20, 21, 23). This evidence concerns the gene CALCA and Headache.