To investigate whether expression of human B4GALNT2 efficiently reduces viral infection of DF-1 cells, DF-1 clone #12 was infected with two subtypes of low pathogenicity avian influenza (LPAI); H5N8 and H9N2 as well as NDV [Multiplicity of infection (MOI) of 0.1]. This evidence concerns the gene B4GALNT2 and viral infectious disease.