Consistent with the findings of this study, adenovirus‐mediated overexpression of Lefty1 has been shown to ameliorate myocardial infarction–induced cardiac fibrosis as well as TGF‐β1‐induced upregulation of Col1 and Col3 in neonatal rat cardiac fibroblasts.42 Here, TGFB1 is linked to myocardial infarction.