By integrated bioinformatics analysis in 2022, Zhang et al. studied the stomach adenocarcinoma and introduced seven hub genes (EWSR1, ESR1, CLTC, PCMT1, TP53, HUWE1, and HDAC1) as related genes to occurrence of stomach adenocarcinoma [65]. The gene discussed is CLTC; the disease is gastric adenocarcinoma.