We observed considerably greater Myc expression in stage I KIPAN and KIRC, with no following stage-wise increases, which is consistent with earlier research on the renal cell carcinoma biomarkers DCLK1 (Doublecortin-like kinase1) and SAA1 (Serum Amyloid A1)19,20. This evidence concerns the gene SAA1 and hereditary clear cell renal cell carcinoma.