PTPRC and metabolic dysfunction-associated steatohepatitis: In addition, we found that there were much more CD45+ cells in NASH livers than in healthy livers (Fig. 2b), and the proportion of PirB+ cells in CD45+ cells was significantly increased (from 19.4 to 40.6%) after a CDHFD (Fig. 2b, c), suggesting an accumulation of PirB+ hepatic immunocytes in NASH.