ITGAM and central nervous system cancer: No significant difference was observed in the inhibition of CD8+ T-cell proliferation between BM-MSC CM and GA-MSC CM (Fig. S1B), though CM from GA-MSCs had a stronger ability to induce the differentiation of CD11b+Gr-1+ MDSCs (Fig. 1D), implying that GA-MSCs might promote glioma progression by inducing MDSCs and promoting the formation of an immunosuppressive microenvironment.