MYO1B has also been found to be strongly expressed in cervical cancer and to be tied with HPV infection, lymphatic metastasis, and case grading, while knockdown of MYO1B in vitro in tumor cells significantly reduced MMP1/MMP9 activity and substantially repressed the proliferation, migration and invasive ability of cervical carcinoma tumor cells38. The gene discussed is MMP1; the disease is cervical carcinoma.